弥可保联合法舒地尔治疗糖尿病周围神经病变疗效观察

Effect of mecobalamin and fasudil for the treatment of diabetic peripheral neuropathy

目的观察弥可保联合法舒地尔治疗糖尿病周围神经病变的临床疗效。方法将60例患者随机分为治疗组和对照组,每组30例,两组患者在治疗时间、降糖药物及饮食与治疗前保持不变,治疗组给予弥可保联合法舒地尔治疗,对照组给予弥可保治疗,两组疗程均为4周。结果治疗组糖尿病周围神经病变症状、体征、神经传导速度明显高于对照组。结论弥可保联合法舒地尔治疗糖尿病周围神经病变疗效显著。

Objective To observe the effect of the combined therapy of mecobalamin and fasudil for the treatment of diabetic peripheral neuropathy（DPN）.Methods Sixty DPN cases were at random divided into treatment group（n=30） and control group（n=30）.The treatment group was given the combined therapy of mecobalamin and fasudil for 4 weeks,during which the attention of diets and control of blood glucose were performed simultaneously in the two groups.The control group was given mecobalamin.Results In the treatment group,the improvement of DPN symptoms and nervous conducting speed were much more obvious than that in the control group.Conclusion The combined therapy of mecobalamin and fasudil is effective on DPN.