重证肺炎中医证候分布规律及症状特点研究

Study on the Distribution and Main Symptom of TCM Pattern of Syndrome of Severe Pneumonia Based on Document Data

目的:基于文献,分析重症肺炎证候分布规律及主要证型的症状特点。方法:采用计算机检索和人工检索相结合方法,检索1981—2008年6月重症肺炎的相关文献,运用频数描述、logistic回归分析和聚类分析方法进行分析。结果:共收集合格文献29篇,55条记录。结果显示,频率较高的证型依次为亡阳证(28.1%)、气阴两虚证(21.8%)、亡阴证(18.75%)、肺热腑实证(18.75%)、厥证(15.62%)、脱证(12.5%)、痰热壅肺证(12.5%)。结合专业知识和聚类结果,筛选痰热壅肺证、阴竭阳脱证、肺热腑实证、热入心包证作为重症肺炎的主要证型,并对证型的主、次症进行了筛选。结论:文献分析总结出了重症肺炎证型分布规律及主要证型症状特点,为进一步研究提供了参考。

Objective：To study the distribution and main symptom of TCM primary pattern of syndrome of severe pneumonia based on document data. Methods：Adapted the combination of computer index and man-made index,by way of document database index on internet,the document data of severe pneumonia syndromes were gathered from 1981 to 2008. 6. The data are analyzed by description,Logistic regression and clustering analysis. Results：55 items of 29 documents were used for analysis. The results indicated that the incidence frequency of some syndromes of severe pneumonia were higher in the distribution of TCM syndrome,they are syndrome of yang death（ 28. 1% ） ,syndrome of qi and yin dificiency（ 21. 8% ） ,syndrome of yin death（ 18. 75% ） ,syndrome of lung-heat and excess disorder of FU-organ（ 18. 75% ） ,syndrome of syncope syndrome（ 15. 62% ） ,syndrome of depletion syndrome（ 12. 5% ） and syndrome of heat-phlegm stagnating the lung（ 12. 5% ）. 4syndromes were screened out as the primary syndrome. They are syndrome of heat-phlegm stagnating the lung,syndrome of yin and yang exhausted simultaneously,syndrome of lung-heat and excess disorder of FU-organ,syndrome of invasion of Pericardium by Heat. Meanwhile,the main symptoms and the sub-symptoms of the primary syndromes were screened out by professional knowledge and statistical analysis. Conclusion：The distribution and main symptom of primary pattern of severe pneumonia syndrome were screened out based on document data,and that would provide references for the next research.