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2009年锦州市第四季度甲型H1N1流感病例监测结果分析 被引量:1

Analysis of Testing Results to Influenza A(H1N1) Virus of Patients in Jinzhou City during the Fourth Quarter in 2009
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摘要 目的对2009年锦州市第四季度甲型H1N1流感病例进行病毒核酸检测,为甲型H1N1流感疫情的防控工作提供数据依据。方法提取样本病毒RNA,对其进行PCR扩增,采用1.5%琼脂糖凝胶电泳,筛选出甲型流感病毒样本,再用实时荧光PCR仪扩增,筛选出甲型H1N1流感病毒阳性样本。综合9至12月四个月的样本分析,把受检人群分成童年(0~6岁)、少年(7~17岁)、青年(18~40岁)、中年(41~65岁)、老年(66岁以后)5个年龄组,计算出各月份、各年龄组人群的患病率。结果童年组、少年组、青年组人群中患病率最高的月份都是10月份,患病率分别是50.00%、42.86%、55.38%;中年组人群中患病率最高的是11月份,患病率为29.03%;老年组人群中各月份患病率普遍偏低,最高是12月份,患病率为13.33%。各月份中,10月份感染甲型H1N1流感病毒的人群患病率最高,为47.59%,其余月份患病率从高到低依次为11月份、9月份、12月份。09年第四季度中,少年组人群的患病率最高,其值为29.05%,其余年龄组人群患病率从高到低依次为青年组、中年组、童年组、老年组。结论通过4个月检测的652个样本,10月份的人群患病率明显增高,这说明甲型H1N1流感病毒传播有一定的季节性变化,节假日期间,适时避免人群大范围流动、过分聚集,对防控流感疫情有一定作用。而对各个年龄组人群患病率分别统计,少年组人群主要是在校学生,学校中人群密集,教室、寝室空气流通不够通畅,因此患病率最高;而老年组人群与外界接触少,患病率低。 Objectives To test Influenza A(H1N1) virus nucleic acid of patients in Jinzhou city during the Fourth Quarter in 2009,and to provide data references for prevention and control of Influenza A(H1N1) epidemics.Methods Extracting virus RNA of patients,Amplifying RNA by RT-PCR,Using 1.5 percent agarose gel electrophoresis to amplified production,Selecting virus RNA of Influenza A,Testing it by real-time PCR,Selecting virus RNA of Influenza A(H1N1).Patients during 9th to 12th month were separated into five year groups by different years:childhood(0-6 years),juvenile(7-17 years)、youth(18-40 years),middle-aged(41- 65 years),elder(over 66 years).Calculating morbidity rate of each month and each year group.Results The highest morbidity rate of childhood,juvenile,youth group was all in 10th month,Respective morbidity rate was 50 percent,42.86 percent,55.38 percent.The highest morbidity rate of middle-aged group was in 11th month,morbidity rate was 29.03 percent.Elder group morbidity rate was lower than other group in each month.The highest morbidity rate of elder group was in 12th month,Morbidity rate was 13.33 percent.In each month,Patients had the highest morbidity rate of Influenza A(H1N1) virus in 10th month,Morbidity rate was 47.59 percent.In the other months,Morbidity rate from high to low was 11th month,9th month and 12th month. During the fourth quarter in 2009,juvenile group had the highest morbidity rate,29.05 percent.In the other year groups,Morbidity rate from high to low was youth,middle-aged,childhood and elder group.Conclusions According to tested 652 doubtful patients during the fourth quarter in 2009,Morbidity rate obviously increased in 10th month,It is illustrated that transmission of Influenza A(H1N1) virus had seasonal variation.During holidays,avoidance of population movement in a large range pay an important role in prevention and control transmission of Influenza A(H1N1) virus.Respective statistics to morbidity rate of different year groups,juvenile group had the highest morbidity rate,because the main juvenile group are students in the school,There are larger population density and less new air in the classrooms.But the elder had lower morbidity rate,because they had less contact to outside.
作者 张振
出处 《疾病监测与控制》 2010年第10期605-607,共3页 Journal of Diseases Monitor and Control
关键词 甲型H1N1流感 病毒核酸检测 年龄组 疫情防控 Influenza A(H1N1) the virus nucleic acid test yeargroups prevention and control of epidemics
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  • 2Cox NJ,Subbarao K.Global epidemiology of influenza: past and present[].Annual Review of Medicine.2000

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