Logistic回归分析大肠腺瘤性息肉数量与癌变的关系

Logistic Analysis on the Association of the Number of Colorectal Polyps with Carcinoma Change

进一步探讨腺瘤性息肉数量与息肉大小、组织学类型的关系及其在制订治疗方案中的价值。临床资料与结果:选用Logistic回归分析法分析了1986～1998年41例病理证实为腺瘤性息肉患者的息肉大小、个数、组织学类型与息肉癌变的关系。发现腺瘤性息肉个数(≥3枚组)、大小(≥2cm组)与息肉癌变显著相关性。特别是个数≥3枚的息肉癌变率高,且多发性息肉的直径多小于1cm。结论:尽管<1cm的息肉癌变机率很小,但其数目的增加同样也会增加癌变率,故对临床检查发现腺瘤性息肉≥3枚的患者,应采取更为积极的治疗手段。

To further understand the relationship between the size, histologic classification, the nu-mber of colorectal adenomatous polyps and their malignant change. Materials and Results: From 1986 through 1998, 41 cases were diagnosed as adenomatous polyps by biopsy. Logistic regression analysis sho-wed that there is a statistically significant higher malignant change rate in the group, whose number of polyps≥3, although the size of the polyps is≤1cm. Conclusions: With the increase of the number of po-lyps, their malignant change rate is also increased despite their small size. Therefore, a more radical ap-proach should be adopted for the patients with multiple polyps.