调节源口服液对高脂大鼠红细胞及肝细胞膜流动性影响的研究

EFFECTS OF THE ORAL SOLUTION OF TOGYRUN ON MEMBRANE FLUIDITY OF ERYTHROCYTES AND MEMBRANE FLUIDITY OF THE HEPATIC CELLS

以实验性高脂血症大鼠为模型研究了调节源口服液对高脂大鼠红细胞膜流动性、肝匀浆膜流动性的影响。并对血脂、肝脂血浆及肝组织中脂质过氧化物（ＬＰＯ）加以测定，结果显示：调节源口服液能显著降低血浆、肝组织中胆固醇含量（Ｐ＜０．０１），也同样能显著降低血浆、肝组织中脂质过氧化物的含量（Ｐ＜０．０１），提高了红细胞膜、肝组织匀浆膜流动性。

In this research, we studied the effects of the oral solution of ToGyRun on membrane fludity of erythrocytes and membrane fluidity of the hepatic cells with hyperlipdaemia rats from the angle of the cholesteral concentration and lipid peroxdation level. The results showed that the oral solution of ToGyRun could significantly decrease the cholesteral concentration and the lipid peroxidation level of serum and liver (P<0. 01),while the membrane fluidity of erythrocytes and membrane fluidity of the hepatic cells significantly lowered (P<0. 03 and P<0. 01).