献血者ABO、RhD血型与HCV感染发生率的关系探讨

Discussion of the correlation between ABO or RhD Blood type and HCV-infection

目的:探讨献血者ABO、RhD血型抗原与HCV感染发生率的关系。方法:抗-HCV检测采用ELISA法;ABO血型和RhD血型鉴定采用试管凝集法,对RhD(-)标本采用抗人球蛋白法确认。结果:850名抗-HCV阳性献血者,按ABO血型分型,其中A型占30.37%、B型占29.73%、O型占31.39%、AB型占8.51%,其分布结果与健康组ABO血型构成相似;850名抗-HCV阳性献血者,按RhD血型分型,其中RhD(+)占98.94%,RhD(-)占1.06%,其分布结果与健康组RhD血型构成有显著差异。结论:献血人群中HCV感染发生率可能与ABO血型抗原无关,而与Rh血型D抗原存在着一定关联。

Objective：To explore the correlation of the ABO blood group,RhD blood group antigens and HCV-infection in blood donor.Methods： Anti-HCV were detected by ELISA method;ABO blood group and RhD blood groups typing were both performed by tube agglutination method;RhD negative samples were confirmed by anti-human globulin method.Results： According to ABO blood type,-850 anti-HCV positive blood donors,of which A-type,B-type,O-type and AB-type were 30.37%,29.73%,31.39% and 8.51% separately.The results were similar to the distribution of blood group composition in health donors;According to RhD blood type,850 anti-HCV positive blood donors,of which RhD positive and RhD negative were 98.94% and 1.06% separately.The results were significant different from the distribution of RhD group composition in health donors.Conclusion： It is possible that HCV-infection have nothing to do with ABO blood group,but associate with RhD blood group antigen.