盐酸氯丙嗪鼻黏膜用药和穴位注射治疗顽固性呃逆疗效比较

Comparison of therapeutic effects on intractable hiccup treated with chlorpromazine hydrochloride nasal mucosa medication and acumen injection

目的比较盐酸氯丙嗪鼻黏膜用药和足三里穴位注射两种给药方式治疗顽固性呃逆的效果。方法将70例顽固性呃逆患者随机分成鼻黏膜用药组和穴位注射组。鼻黏膜用药组35例给予盐酸氯丙嗪滴鼻,12.5mg(双侧总量)/次,4次/d;穴位注射组35例给予盐酸氯丙嗪足三里穴位注射,25mg(双侧总量)/次,2次/d。两组疗程均为3d。结果鼻黏膜用药组和穴位注射组总有效率分别为97.1%和91.4%,经统计学处理,两组差异无统计学意义(P>0.05)。结论盐酸氯丙嗪注射液两种给药方式治疗顽固性呃逆均有较好的疗效。其中鼻黏膜用药方式具有简便、速效和无痛苦的特点,更易于为患者所接受。

Objective Treat intractable hiccup with two different therapy-nasal mucosa medication chlorpromazne hydrochloride and zusanli acumen injection to make a comparison. Methods 70 cases of intractable hiccup patients were randomly divided into nasel mucosa medication group and acumen injection group. 35 cases in nasel mucosa medication group wrer treated with chlorpromazine hydrochloride droped on nasel mucosa, 12. 5 mg（ total of two sides） being given four times daily; 35 cases in acumen injection group were treated with chlorpromazine hydrochloride injected zusanli acumen,25 mg（ total of two sides） being given two times daily; 2 groups were treated 3 days. Results The total effective rate in nasel mucosa medication group and acumen injection group was 97. 1% and 91. 4% respectively. After statistical analysis,the difference of two groups was not statistically significant（ P 0. 05） . Conclusion Both of nasel mucosa medication and acumen injection had better clinical therapeutic effects on intractable hiccup treated with chlorpromazine hydrochloride injection. Nasel mucosa medication had convenient,available and no pain and patients accepted easily.