期刊文献+

ECLIA检测CA15-3和CEA在乳腺癌术后患者随访中的临床价值

下载PDF
导出
摘要 目的分析乳腺癌术后在放化疗前后及其复发转移时患者血清CA15-3和CEA的变化情况,探讨患者乳腺癌术后二者在随访中的临床应用价值。方法应用电化学发光法(ECLIA)对73例不同时期乳腺癌术后患者进行血清CA15-3和CEA的水平检测,并与69例正常人比较。结果乳腺癌术后放化疗治疗前患者血清CA15-3和CEA水平显著高于对照组和放化疗治疗后组(P<0.01);而放化疗治疗后组与对照组间无明显差异(P>0.05);复发转移组患者血清CA15-3和CEA水平明显高于对照组和治疗后组(P<0.01)。结论血清CA15-3和CEA的检测对于乳腺癌术后疗效观察随访具有重要的临床意义。
出处 《中国现代药物应用》 2010年第21期77-78,共2页 Chinese Journal of Modern Drug Application
关键词 乳腺癌 CA15-3 CEA
  • 相关文献

参考文献3

二级参考文献23

  • 1王晓春,刘运江,刘现义,李中.hMAM mRNA和CK19 mRNA联合检测乳腺癌骨髓微转移[J].中华肿瘤防治杂志,2007,14(9):676-679. 被引量:15
  • 2万文徽,李吉友.肿瘤标志的临床应用[J].中华医学检验杂志,1997,20(1):49-51. 被引量:180
  • 3Hennessy B T, Hortobagyi G N, Rouzier R,et al. Outeome after pathologic complete eradication of cytologically proven breast cancer axillary node metastases following primary chemotherapy [J]. J Clin Oncol,2005,23(36) :9304-9308.
  • 4Molina R, Jo J, Filella X, et al. C-erbB-2 CEA and CA153 serum levels in the early diagnosis of recurrence in breast cancer patients [J]. Anticancer Res,1999,19:2551-2555.
  • 5Pentheroudakis G, Malamou-Mitsi V, Briasoulis E, et al. The neutrophil, not the tumor, serum CA15-3 elevation as a result of granuloeyte-colony-stimulating factor-induced neutrophil MUC1 overexpression and neutrophilia in patients with breast carcinoma receiving adjuvant chemotherapy [ J ]. Cancer,2004,101 ( 8 ) : 1767 - 1775.
  • 6Martinez-Trufero J, de Lobera AR, Lao J, et al. Serum markers and prognosis in locally advanced breast cancer [ J ]. Tumori ,2005,91 ( 6): 522 - 530.
  • 7Bartseh R, Wenzel C, Plusehnig U, et al. Prognostic value of monitoring tumour markers CA15-3 and CEA during fulvestrant treatment [ J ]. BMC Cancer, 2006,6 (1) :81 -87.
  • 8Ren J, Agata N, Chen D, et al. Human MUC1 carcinomaassociated protein confers resistance to genotoxic anticancer agents [ J ]. Cancer Cell,2004,5 (2):163 - 175.
  • 9Sonoo H, Kurebayashi J. Serum tumor marker kinetics and the clinical course of patients with advanced breast cancer [J]. Surg Today, 1996,26(4) :250 - 257.
  • 10Sjostrom J, Alfthan H, Joensuu H, et al. Serum tumour markers CA15-3, TPA, TPS, hCGbeta and TATI in the monitoring of chemotherapy response in metastatic breast cancer [ J ]. Scand J Clin Lab Invest, 2001,61 ( 6 ) : 431 -441.

共引文献198

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部