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趋化因子及其受体在口腔扁平苔藓中的作用

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摘要 口腔扁平苔藓(Oral lichen planus,OLP)是常见的口腔黏膜病之一,其主要病理变化为基底细胞层液化变性以及上皮固有层内大量淋巴细胞呈带状浸润。WHO将之定义为癌前状态,OLP的病因及发病机制目前仍不明确,但大量研究证实OLP的发生发展与T细胞介导的免疫应答密切相关。趋化因子是一类特殊的细胞因子,在淋巴细胞的迁移和激活中起着极其重要的作用。
作者 崔继丽 周刚
出处 《口腔医学研究》 CAS CSCD 北大核心 2010年第5期761-763,共3页 Journal of Oral Science Research
基金 国家自然科学基金资助项目(编号:30572041 30973311)
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