髓核及侧隐窝注射臭氧治疗腰椎间盘突出症

Percutaneous oxygen-ozone injection into both the nucleus pulposus and lateral recess for the treatment of lumbar disc herniation:a clinical analysis

目的探讨经皮穿刺髓核及侧隐窝注射臭氧治疗腰椎间盘突出症的临床疗效。方法 88例经CT或MRI证实为腰椎间盘突出症患者进行髓核及侧隐窝注射臭氧作为研究组,并以74例腰椎间盘突出症仅作髓核注射臭氧患者作为对照组。结果髓核及侧隐窝联合注射对腰椎间盘突出症的患者症状缓解更快、临床疗效持续更长,随访6个月研究组临床疗效达84.1%;对照组为64.9%。统计学分析显示术后1、2和6个月研究组有效率均高于对照组(χ2=4.09,P=0.043;χ2=4.62,P=0.032;χ2=4.38,P=0.036),差异具有统计学意义。结论髓核内及侧隐窝联合注射臭氧比单一髓核内注射臭氧更加有效。

Objective To discuss the therapeutic effects of oxygen-ozone injection into both the nucleus pulposus and lateral recess in treating lumbar disc herniation.Methods Eighty-eight patients with CT-proved or MRI-proved lumbar disc herniation were used as study group,who received the treatment of percutaneous oxygen-ozone injection into both the nucleus pulposus and lateral recess.Another 74 patients with lumbar disc herniation were used as control group,who received percutaneous oxygen-ozone injection into the nucleus pulposus only.Results After the treatment,the patients in the study group were relived from their symptoms much faster and the clinical effect was kept much longer.At 6 month after the procedure,the clinical therapeutic efficiency of study group was 84.1%.The effective rates of study group at 1,2 and 6 months after the operation were much higher than those of control group,the differences between two groups were statistically significant（χ2 = 4.09,P = 0.043;χ2 = 4.62,P = 0.032;χ2 = 4.38,P = 0.036,respectively）.Conclusion For the treatment of lumbar disc herniation percutaneous oxygen-ozone injection into both the nucleus pulposus and lateral recess is more effective than injection into nucleus pulposus only.（J Intervent Radiol,2010,19：820-823）