新型腺苷A_(2A)受体激动药瑞加诺生在心肌灌注显像中的应用

Use of regadenoson,a new adenosine A_(2A) receptor agonist,in myocardial perfusion imaging

心肌灌注显像在测定冠状动脉病变、危险性测定、判断心肌存活、评价治疗效果中发挥重要作用。瑞加诺生是一个新型的腺苷A2A受体激动药。与在心肌灌注显像中用于激发的经典药物腺苷相比,瑞加诺生不引起支气管收缩,不引起房室传导阻滞,具有作用显著、不良反应小等优点。

Myocardial perfusion imaging plays very important role in detecting coronary artery disease,assessing risk,detecting viable myocardium,evaluating the effects of therapeutic interventions.Regadenoson is a new adenosine A2A receptor agonist.Compared with adenosine,a typical drug used for myocardial perfusion imaging,regadenoson does not cause bronchial constriction and atrial-ventricular block.It has the advantage of good efficacy and less side effects.