快动眼睡眠相关阻塞性睡眠呼吸暂停低通气综合征的睡眠监测特点

Polysomnographic features of obstructive sleep apnea and hypopnea syndrome associated with rapid eye movement

目的探讨与快动眼(rapid eye movement,REM)睡眠期密切相关的阻塞性睡眠呼吸暂停低通气综合征(OSAHS),即REMOSAHS患者的临床及睡眠监测特点。方法回顾在我院进行多道睡眠图(PSG)监测诊断为OSAHS的患者,根据REM睡眠期呼吸暂停低通气指数(AHIREM)和慢动眼睡眠期(non-rapid eye movement,NREM)呼吸暂停低通气指数(AHINREM)将其分为两组,AHIREM/AHINREM>2为REMOSAHS组,AHIREM/AHINREM≤2为NREMOSAHS组,比较REMOSAHS与NREMOSAHS临床睡眠监测指标的差异。结果 159例OSAHS患者中,REMOSAHS占19.5%,其中男性占58.1%,女性占41.9%;REMOSAHS组与NREMOSAHS组年龄比较差异具有显著性[(34.9±13.5)岁vs(39.6±9.6)岁];两组体块指数(BMI)比较,差异无显著性[(28.1±2.5)kg/m2vs(28.8±3.4)kg/m2];两组总睡眠呼吸暂停低通气指数(AHITST)比较,差异具有显著性[(32.2±29.8)次/hvs(53.0±27.5)次/h]。结论 REMOSAHS女性与男性发病率相近,且年龄较轻,病情较轻。

OBJECTIVE To study the clinical and polysomnograph（PSG）characteristics of patients with REM-related obstructive sleep apnea and hypopnea syndrome（REM OSAHS）.METHODS 159 patients with OSAHS were diagnosed with overnight PSG.REM OSAHS was defined as an AHIREM/AHINREM ratio2;NREM OSAHS was defined as an AHIREM/AHINREM ratio≤2.The clinical and PSG results were compared between the two groups.RESULTS 19.5% of cases fulfilled the REM OSAHS criteria with 58.1% in men and 41.9% in women.There were significant differences between patients with REM OSAHS and NREM OSAHS in age [（34.9±13.5）vs（39.6±9.6）years] and AHI [（32.2±29.8）vs（53.0±27.5）times/h].REM OSAHS patients were younger and had lower AHI.No difference was found in BMI [（28.1±2.5）vs（28.8±3.4）kg/m2].CONCLUSION There was an equal incidence of REM OSAHS in women and men.The patients with REM OSAHS were younger and less severe.