腺苷蛋氨酸联合熊去氧胆酸治疗淤胆型病毒性肝炎的疗效观察

Ademetionine 1,4-Butanedisulfonate Enteric Coated Tabletsto and Ursodeoxycholic Acid combination therapy-the cholestatic viral hepatitis

目的:评价腺苷蛋氨酸联合熊去氧胆酸治疗淤胆型病毒性肝炎的临床价值。方法:将淤胆型肝炎132例随机分为治疗组和对照组各66例。治疗组用腺苷蛋氨酸及熊去氧胆酸治疗4周,对照组用门冬氨酸钾镁治疗4周,比较两组治疗效果。结果:治疗组临床症状消失率、皮肤瘙痒的有效率、肝消毒有效率、肝功能改善率均优于对照组(P<0.05或0.01)。结论:腺苷蛋氨酸联合熊去氧胆酸是治疗淤胆型病毒性肝炎较好方法。

Objective：To study the combined Ademetionine 1,4 -Butanedisulfonate Emetic Coated Tabletsto and ursodeoxycholic acid treatment of cholestatic viral hepatitis and single injection with the efficacy of potassium magnesium aspartate injection observation. Methods： Patients with no static point adenosylmethionine freeze - dried powder combined oral ursodeoxycholic acid, the control group only treated with potassium magnesium aspartate injection. Results： Ademetionine 1,4 - Butanedisulfonate Enteric Coated Tabletsto combined ursodeoxyeholic acid treatment of acute and chronic cholestatic hepatitis than single injection of potassium magnesium aspartate can improve liver function. Condusion：Ademetionine 1,4 - Butanedisulfonate Enteric Coated Tabletsto and ursodeoxycholic acid had no obvious toxicity, its safety and tolerability was good. In the treatment of cholestatic viral hepatitis, the Ademetionine 1,4 - Butanedisulfonate Enteric Coated Tabletsto joint UDCA is ideal clinical treatment.