摘要
In recent years,intravascular ultrasound（IVUS） follow-up is always used in the evaluation of the development of atherosclerosis,and it can also be used as the endpoint of drug therapy in clinical observation.Since 1994,the first statin lipid-lowering 4S experiment results was reported,the following statin for lipid-lowering tests represented by REVERSAL PROVE-IT,TNT,IDEAL,ASTEROID and JUPITER strongly confirmed that further reduce the efficacy of low-density lipoprotein cholesterol（LDL-C）（to enhance the lipid-lowering treatment） access to increase effect of the cardiovascular protection and also reverse the plaques＇ progress.But scholars＇ opinions on the merits and demerits of enhance statin cholesterol-lowering therapy has been in debate.We review the recent work on statins and reversal of arterial plaques for a number of clinical studies.
In recent years,intravascular ultrasound（IVUS） follow-up is always used in the evaluation of the development of atherosclerosis,and it can also be used as the endpoint of drug therapy in clinical observation.Since 1994,the first statin lipid-lowering 4S experiment results was reported,the following statin for lipid-lowering tests represented by REVERSAL PROVE-IT,TNT,IDEAL,ASTEROID and JUPITER strongly confirmed that further reduce the efficacy of low-density lipoprotein cholesterol（LDL-C）（to enhance the lipid-lowering treatment） access to increase effect of the cardiovascular protection and also reverse the plaques＇ progress.But scholars＇ opinions on the merits and demerits of enhance statin cholesterol-lowering therapy has been in debate.We review the recent work on statins and reversal of arterial plaques for a number of clinical studies.
