珠海市120例甲型H1N1流感病例的回顾性分析

CIinical Features of 120 Cases of Influenza A(H1N1) Virus Infection in Zhuhai

目的分析甲型HlN1流感确诊病例的临床特点,为以后临床诊治提供依据。方法对2009年5月-2010年3月收治的120例甲型H1N1流感病例进行回顾性分析。结果 120例甲型H1N1流感病例以本土病例为主,占93%,5～49岁是主要的发病人群,单纯甲型H1N1感染67例,危重症2例;95%以上的患者有突出的上呼吸道症状。心肌酶谱异常达65%,轻度低钾血症达26%。淋巴细胞百分率低于正常出现在一般病例的急性期和危重症病例的进展期;高于正常见于疾病的恢复期。结论珠海市甲型H1N1流感患者呼吸道症状突出,部分患者出现心肌酶谱改变和低钾血症,经积极治疗,预后良好;淋巴细胞百分率的高低对疾病状态的评价有一定的提示作用。

Objective To analyze the clinical features of confirmed Influenza A （ H1 N1 ）. Methods The clinical data of 120 patients with confirmed Influenza A（ H1N1 ） admitted and treated during the period from May 2009 to March 2010 were analyzed retrospectively. Results Domestic cases account for 93% of all patients,who were 10 months to 52 years old. There were 67 cases suffered with simple influenza A（H1N1 ） virus infection and 53 with complications,including 2 severe cases and 10 pregnant women. Patients typically present with fever（ 100% ）, congestion of throat （96%）, coughing （83 % ）, rough breath sounds （58 % ）, antiadoncus（56% ） and sore throat（52% ）. Increased myocardial enzymes were detected in 66 of 102（65% ） patients and mild hypokalemia in 24 of 93 （26%）. Depressed percentage of lymphocytes present when patients were in acute or aggressive stage, and elevated one does when they in convalescence. Conclusion The patients suffered with novel influenza A （ H1 N1 ） virus infection in Zhabai possessed remarkable clinical manifestations of respiratory system, some of them got abnormal myocardial enzymes and mild hypokalemia, but all had favorable prognosis. Percentage of lymphocytes may be a valuable index of evaluating the state or stage of patients with influenza A（ H1N1 ）.