不同病程强迫症患者临床特征比较分析

Comparison of Clinical Features between Patients with Long-term Course and Short-term Course Obsessive-Compulsive Disorder(OCD)

目的本研究旨在分析不同病程强迫症患者的临床特征。方法本研究采用《症状自评量表》(SCL-90)评估两组强迫症患者的心理状况,同时采用《艾森克个性问卷》(EPQ)进行个性测验,通过临床观察评估疗效,利用SPSS统计软件进行相关t检验、χ2检验等统计分析。结果长病程组强迫症患者SCL-90评分中躯体化、强迫、人际关系、抑郁、偏执和精神病性等六项因子分均高于短病程组评分,两者差异具有统计学意义(P<0.05);EPQ测验显示长病程组E、P评分亦高于短病程组,两者差异具有统计学意义(P<0.05),长病程者情绪稳定性更差,同时更多具有孤僻、爱独处、不关心人等特点;临床疗效方面,两组治疗有效率差异无统计学意义(P>0.05),但长病程患者痊愈率(2.4%)低于短病程者(8.2%),两者差异具有统计学意义(P<0.05)。结论长病程强迫症患者临床症状较短病程者更为严重和复杂,临床痊愈率更低。

Objective To study the clinical features of patients with different course of obsessive-compulsive disorder（ OCD ）.Methods The psychologic status and personality of patients in both groups were assayed by using setf-report symptom inventory SCL-90 and Eysenck Personality Questionnaire（EPQ） ,respectively. The therapeutic effect was assessed by clinical observation. Statistical analysis like t test and χ^2 test was performed in SPSS. Results Patients with long-term course got higher scores on somopsychosis, compulsivity, relationship between people, dumps, anxiety, insane and crankiness than that patients with short-term course, the difference had statistical significance （P 〈 0.05 ）. The E and P valiues were also higher in long-term course patients than that in short-term course patients, the difference had statistical significance （ P 〈 0.05 ）. There was no statistical difference between the effective rates of the two groups （ P 〉 0. 05 ）, but the recovery rate was lower in long-term course patients （ 2.4% ） as compared to that of.patients with short-term（8.2% ）, the difference had statistical significance（ P 〈 0.05 ）. Conclusion Clinical symptoms of patients with long-term course OCD were severe and complex compared with long-term course OCD. The clinical cure rate is lower.