颅咽管瘤:MRI和CT表现及与病理对照

Craniopharyngioma:MRI and CT manifestations with correlation to pathologic finding

目的：分析颅咽管瘤ＣＴ、ＭＲＩ特征，探讨影像学表现和病理间的联系，尤其是ＭＲＩ的Ｔ１高信号的产生基础。方法：ＣＴ及ＭＲＩ检查２１例颅咽管瘤患者，均经手术病理证实，囊液进行内容物的镜下分析。结果：实质性３例，囊性、囊实性１８例，其囊液１１例可见Ｔ１加仅像高信号，且不受ＭＲＩ脂肪抑制术影响，病理囊液内均可见胆固醇，Ｔ１高信号的囊液内还可见蛋白物、游离血红蛋白等。结论：ＣＴ、ＭＲＩ相结合可以准确诊断颅咽管瘤，颅咽管瘤囊液内的高信号主要与囊液内的蛋白质有关，与胆固醇类物关系较小。

Purpose:To analyse the CT and MRI characteristics of craniopharyngioma and investigate the realtionships between image manifestations and pathologic findings.Methods:21 cases of craniopharyngioma confirmed by operation and pathology underwent CT and MRI examination.The cystic fluid were analysed microscopically.Results:3 cases were solid in nature and 18 cases were cystic or solid cystic. 11 cases of the cystic fluid revealed as high signals on MRI T 1 weighted images and couldn't be suppressed by fat suppression.On pathologic study,cholesterol can be found in all the cystic fluid.Protein and free hemoglobin were found only in the cystic fluid which manifested as high signals on MRI T 1 weighted images.Conclusion:The craniopharyngioma could be diagnosed accurately by combined using of CT and MRI. The high signal intensity were associated mainly with protein,and less related to the cholesterol.