摘要
目的证实膜引导性组织再生现象存在于骨缺损的愈合过程中，并探讨其机理。方法采用新西兰大白兔为实验对象，将兔桡骨制成１ｃｍ缺损，一侧用羟基磷灰石／聚乳酸膜（ＨＡ／ＰＬＡ）包绕缺损，另一侧作为对照，通过Ｘ线片、大体观察及病理检查等观察两侧桡骨愈合情况。结果对照侧均呈现骨不愈合现象，实验侧有不同程度的骨愈合现象。结论膜技术的应用有利于骨缺损的愈合。
Objective To confirm membrane guided tissue regeneration in the healing course of segmental bone defects and study the mechanism.Methods Segmental,1 cm osteoperiosteal defects were produced in both radii of 12 rabbits.One side was covered with hydroxyapatite/polylactic acid(HA/PLA) membrane encapsulated as a tube.The contralateral side served as an untreated control.Healing courses were detected by radiographic and histologic examinations.Results All control sides showed nonunion,whereas there were consistent healing pattern in test sides.Conclusion Membrane technique can promote bone regeneration.
出处
《中国修复重建外科杂志》
CAS
CSCD
1999年第3期129-132,共4页
Chinese Journal of Reparative and Reconstructive Surgery
基金
国家自然科学基金
关键词
引导性
骨组织再生
膜技术
聚乳酸
骨缺损
修复
Guided bone regeneration Membrane technique Polylactic acid Hydroxyapatite Foundation item: National Natural Science Foundation of China(39270680)
