牙周鲁菲尼神经末梢形态和功能的影响因素

Factors influencing the morphology and function of periodontal Ruffini endings

牙周鲁菲尼神经末梢是牙周膜内的一种低阈值慢适应力感受器,具有典型的形态特征。在牙周鲁菲尼神经末梢的发育、再生和改建中,神经营养因子及其受体起关键性作用,牙周组织中的终末神经膜细胞也可能参与其中。咬合关系变化和正畸移动力等牙周力环境的改变,可引起牙周鲁菲尼神经末梢的形态和功能改变。本文就其形态学特征及其与神经营养因子、终末神经膜细胞、力环境改变的关系等研究进展作一综述。

The periodontal Ruffini endings are low-threshold and slowly adapting mechanoreceptors which display typical morphological features. In the development,regeneration and reconstruction of the periodontal Ruffini endings,neurotrophic factors and their receptors play crucial roles,and terminal neurolemmal cells in the periodontium might also make important contributions. The morphology and function of periodontal Ruffini endings can be changed by the alterations in the mechanical environment of the periodontium,such as occlusal changes and orthodontic tooth movement. The present review summarized the recent advancements on the morphological characte-rristics of periodontal Ruffini endings and their relationship to neurotrophic factors,terminal neurolemmal cells and mechanical environment changes.