摘要
目的探讨清空分散片对小鼠偏头痛模型的作用。方法通过观察清空分散片对利血平所致小鼠偏头痛模型的影响了解清空分散片对小鼠偏头痛模型的作用。结果清空分散片有明显对抗利血平所致小鼠偏头痛模型的体重下降、提高模型小鼠鼠尾的光照痛域值,延长模型小鼠凝血时间,调节模型小鼠血清中五羟色胺过度降低的作用。结论清空分散片对利血平所致小鼠偏头痛模型有治疗作用,为清空分散片在临床上治疗偏头痛提供了药效学实验依据。
Objective To observe effects of Qingkong disket on migraine of mice induced by reserpine.Methods Using the migraine of mice induced by reserpine to observe the influence of Qingkong disket on the model mice.Results The Qingkong disket could obviously strengthen weight,elevate pain threshold,prolong coagulation time,and prevent excessive decrease in 5-HT of migraine mice induced by reserpine.Conclusion The Qingkong disket has curative effect on migraine of mice induced by reserpine,and provide medical basis for its clinical use.
出处
《实验动物科学》
2010年第5期13-15,共3页
Laboratory Animal Science
