3,6-二烷硫基-1-苯基-吡唑并[3,4-d]嘧啶-4-酮衍生物的合成与除草活性

Synthesis and Herbicidal Activity of 3,6-Dialkylthio-1-phenyl-pyrazolo[3,4-d]pyrimidin-4-ones

通过3-甲硫基-1-苯基-吡唑并[3,4-d]嘧啶-6-硫酮和卤代烃RX(BrR'Br)亲核取代反应合成了16种标题化合物,其结构使用元素分析、IR,1H NMR及LC-MS进行了表征.初步的生物活性测试表明,部分化合物对单、双子叶植物根的生长具有优异的抑制作用.

Sixteen novel 3,6-dialkylthio-1-phenyl-pyrazolopyrimidin-4-ones were synthesized from the intermediate 3-alkylthio-1-phenyl-pyrazolopyrimidin-6-thiones and RX or BrR＇Br.All compounds synthesized were identified by ^1H NMR,IR and MS techniques.Preliminary bioassay results show that some of these compounds have better inhibitory effect against the roots of rape and barnyard grass.