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胃癌患者血清IL-6、IL-8、TNF-α水平变化及意义 被引量:2

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摘要 目的观察胃癌患者血清IL-6、IL-8和肿瘤坏死因子α(TNF-α)水平变化,并探讨其临床意义。方法采用ELISA法测定50例胃癌患者(观察组)和20例健康对照者(对照组)血清IL-6、IL-8和TNF-α水平。结果观察组患者血清IL-6、IL-8和TNF-α水平明显高于对照组(P均<0.05)。观察组Ⅲ、Ⅳ期胃癌患者血清IL-6、IL-8和TNF-α水平明显高于Ⅰ、Ⅱ期患者(P均<0.05)。结论 胃癌患者IL-6、IL-8和TNF-α水平增高。这可能与胃癌的发生、发展有关。
作者 孙宝峰
机构地区 兖矿集团总医院
出处 《山东医药》 CAS 北大核心 2010年第38期69-70,共2页 Shandong Medical Journal
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