宫颈上皮类瘤变344例治疗随访观察

The treatment and observation of 344 cases of CIN.

目的了解宫颈癌早期筛查及宫颈上皮类瘤变(CIN)治疗随访情况,以便进一步做好宫颈癌早查早治的工作。方法对2 463名妇女行液基细胞学(TCT)检测,其中有601人自愿行人乳头状瘤病毒(HPV)筛查,结果异常者行阴道镜检查。阴道镜检查异常者,行宫颈活检确诊。对CINⅠ级以上病人行手术治疗,术后3个月、6个月、9个月、12个月随访一次,复查TCT、HPV及阴道镜。结果 CINⅠ度304例,CINⅡ度和CINⅢ度各20例。术后1年复查,TCT转为正常的有190例,治愈率是99.5%(190/191),1例CINⅡ的病人,术后半年及术后9个月复查TCT都正常,1年后复查又转为异常。结论通过筛查,可早期发现CIN。利用高频电波刀的电圈切除(LEEP)及宫颈冷刀锥切治疗CIN效果满意,可将宫颈癌扼杀在此阶段。

Objective To study test early of cervical cance and information of CIN be treated and visting,than,It be made better to test and treat early of cervical cance.Methods Test TCT and HPV with 2 463 women,Result them of result strange need to vagindl mirror test,The disease of CINⅠ ～ Ⅲ be treated,visting in third month,sixth month,ninth month,twelfth month,Reexamine TCT and HPV and vagindl mirror.Re-sults Degree of 304 cases of CIN Ⅰ,CIN Ⅱ degree and the degree of the 20 cases of CIN Ⅲ.1 year after review,TCT into a normal 190 ca-ses,cure rate was 99.5%（190 /191）,1 case of CIN Ⅱ patients,after six months and after 9 months later TCT were normal,1 year after the re-view and into an exception.Conclusion Through screening,early detection of CIN.Use of high frequency radiosurgical knife in the loop electro-surgical excision（LEEP） and cold-knife conization of cervical satisfactory treatment of CIN,cervical cancer can be killed at this stage.