摘要
糖尿病肾病(DN)是一种常见临床疾病。微量白蛋白尿是诊断DN及临床分期的标志物,但也受许多因素影响,用于预测、判断DN的发生、发展有一定的局限性。DN患者血浆中B型脑利钠肽、同型半胱氨酸水平显著增加,同型半胱氨酸与DN患者蛋白尿有相关性,B型脑利钠肽与DN患者肾功能有明显联系,二者指标联合检测用于DN患者的诊治过程中有重要意义。其二者可作为血浆标志物用于DN的诊断、严重程度的判断、临床治疗效果及预后的评估。
Diabetic nephropathy（ DN） is a common medical condition. Urine microprotein is a marker for diagnosing and grouping DN. However,it is affected by many factors. There is a limitation in judging and predicting the relationship of DN. In DN patients,plasma B-type natriuretic peptide（ BNP） and homocysteine are remarkably increased,whereas homocysteine is associated with urine microprotein and BNP is with renal function. The two markers play an important role in type 2 DN and may be used in the diagnosis,evaluation, assessment and prediction of type 2 DN as a plasma marker.
出处
《医学综述》
2010年第21期3306-3308,共3页
Medical Recapitulate
基金
2010年上海市青浦区科学技术发展基金
关键词
脑利尿钠肽
同型半胱氨酸
糖尿病肾病
微量白蛋白
肌酐
brain natriuretic peptide
Homocysteine
Diabetic nephropathy
Urine micro protein
Creatinine
