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冠状动脉介入治疗中造影剂对肾功能损害的临床分析

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摘要 目的 探讨造影剂在冠状动脉介入治疗中对肾功能的不良影响.方法 将我院行冠状动脉介入治疗术者360例,其中术前肾功能正常者240例,选用非离子低渗造影剂,术前肾功能异常者120例,使用等渗造影剂,并分别于实施介入治疗前、治疗后第1、2、6d检测肾功能指标.结果 术前肾功能正常者造影剂肾病发生率为4.58%;其患造影剂肾病者与未患造影剂肾病者在糖尿病,造影剂用量和术前补液量等方面具有显著差异(P<0.05).术前肾功能异常者造影剂肾病发生率为1.67%;其患造影剂肾病者与未患造影剂肾病者在糖尿病,造影剂用量和术前补液量等方面也具有显著差异(P<0.05).两种造影剂对肾功能的影响也存在差异.结论 等渗造影剂对冠状动脉介入治疗患者的肾毒性比低渗造影剂低,肾功能异常者在行冠状动脉介入治疗术时使用等渗造影剂更安全.
作者 谭保平
出处 《医学新知》 CAS 2010年第5期504-505,共2页 New Medicine
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