非离子表面活性剂浊点萃取甘草酸体系的特性

The Cloud Point Extraction of Glycyrrhizic Acid by a Non-ionic Surfactant System

用非离子表面活性剂TritonX-100和NaCl盐溶液在一定温度下形成的浊点体系为萃取介质,重点研究了浊点萃取甘草酸过程中凝聚相及水相的谱学性质和微观结构。结果表明,随着温度的升高,红外谱图中O—H的振动吸收峰和C—O骨架伸缩振动峰会向高波数移动,而在浊点温度时,波数变化明显。浊点体系的主体相具有粒度性质特征,吸附溶质后的凝聚相胶团粒径增大。随着甘草酸浓度的升高,胶团从7.7nm增大至20nm以上,有类似聚集的现象。

The cloud point system containing Triton X-100 and NaCl at given temperatures was useed as an extracting medium.A detailed study on spectral characteristics and microstructures has been carried out to investigate the process of cloud point extraction of glycyrrhizic acid（GA）.The results showed that the wave numbers of H—O and C—O stretching vibration bands in the Fourier transform infrared spectra increased with increasing temperature.Near the cloud point,this change has been strengthened.Main phase bodies in cloud point system have droplet-distribution characteristics and the micelle size in coacervate phase was enlarged after adsorping more GA.Under high concentration of GA,this phenomenon was attributed to the inter crosslinking of micelles in the coacervate phase.