情绪记忆对精神分裂症患者风险决策的影响

目的 探讨情绪记忆对精神分裂症患者风险决策能力的影响.方法 精神分裂症患者（SC组）40例和健康对照（HC组）40例,采用情绪记忆和风险决策两方面的实验任务,比较两组情绪记忆的结果和执行风险决策的能力.结果 两组情绪图片的评分差异无统计学意义（P〉0.05）,对负性和中性图片的回忆率差异均有统计学意义（t=-4.44,P〈0.01;t=-3.32,P〈0.01）;与HC组比较,SC组在奖赏后和惩罚后的风险选择频率均显著升高（t=-2.29,P〈0.05;t=-6.18,P〈0.01）.结论 精神分裂症患者追求高奖赏,惩罚后风险选择的抑制效应消失,且患者风险决策能力的损害与其情绪记忆功能受损密切相关.

Objective To explore the relativity between emotional memory and risk -taking in schizophrenia patients. Methods Forty schizophrenic patients and forty healthy subjects were given the emotional memory test and risk -taking task. Results There was no significant difference between patients with schizophrenia and control 1 subjects in rating the negative, neutral and positive pictures （P 〉0. 05 ） ; Schizophrenic patients had worse recall for both negative and neutral scenes than control subjects at the emotional memory test （t = -4.44,P 〈 0. 01 ;t = -3.32,P 〈 0. 01 ） ; the risky response rate after reward and punishment of the patients with Schizophrenia significantly higher than that of the HC group （ t = - 2.29, P 〈 0. 05 ; t = - 6. 18, P 〈 0.01 ）. Conclusion The patients with Schizophrenia have a specific deficit in risk - taking, i.e. an inhibition effect of punishment, reduced sensitivity to punishment but increased sensitivity to reward. The emotional memory plays an important role in risk - taking processes.