间歇充气加压治疗对GICU患者下肢深静脉血栓的预防作用

The efficacy of IPC in the prevention of lower deep wein thrombosis in GICU.

目的探讨间歇充气加压治疗(IPC)对综合重症监护室(GICU)患者下肢深静脉血栓(DVT)的预防作用。方法前瞻性随机对照临床试验。将2009年1月～2010年1月入GICU时未使用抗凝药物的患者随机分配到IPC组和对照组。IPC组从患者入ICU当日直到离开ICU予IPC预防下肢DVT;对照组不予任何措施预防DVT。以28d为观察期,比较观察期内两组患者下肢DVT发生率、带机时间、ICU住院日、ICU死亡率。结果在观察期内,与对照组相比,IPC可以显著降低下肢DVT发生率,IPC组带机时间及ICU住院日、ICU死亡率低于对照组,但差异无统计学意义。结论在GICU中IPC是预防DVT发生的一种安全有效的措施。在本研究尚未发现IPC能显著降低GICU患者带机时间、ICU住院日、ICU病死率。

Objective To evaluate the efficacy of Intermittent pneumatic compression（IPC） in the prevention of lower deep vein thrombsis（DVT） in general intensive care unit（GICU）.Methods We conducted a prospective,randomized,controlled,unblinded stdudy.Patients were randomly assigned to receive or not receive IPC after GICU admission.Patients under anticoagulation medicine therapy were not eligible.To compare the rate of DVT,ICU stay,mechanical ventilation day and ICU mortality rate during the subsequent 28 days.Results Compared with the controlled group,IPC group had a significantly lower rate of lower DVT.The days of ICU stay and mechanical ventilation in the IPC group were shorter and the ICU mortality rate were lower than controlled group,but both were not statistically significant.Conclusion IPC can prevent lower DVT efficaciously and safely in GICU.No significant effects of IPC on ICU stay,mechanical ventilation day and ICU mortality have been found in this study.