急性重症胰腺炎腹内压、腹围与APACHE评分的相关性研究

Relevant research of intra-abdominal pressure,abdominal circumference and APACHE score forsevereacute pancreatitis.

目的通过对ICU急性重症胰腺炎患者腹内压的监测数据,来推断它在急性重症胰腺炎的严重程度和疗效分析中的临床意义。方法根据我科2005年5月～2009年5月收治急性重症胰腺炎28例(死亡组10例,治愈组18例)的腹内压监测数据,分别比较两组的腹内压监测和腹围与APACHE-II评分的相关性。结果治愈组腹内压与A-PACHE-Ⅱ评分的回归方程是Y=1.406+0.690X,相关系数r=0.646,P<0.001,有明显相关性;腹围与APACHE的相关系数r=0.175,P=0.048,有一定相关性。死亡组结果:腹内压与APACHE-Ⅱ评分的回归方程是Y=14.767+0.471X,相关系数r=0.387,P=0.008,有明显相关性;腹围与APACHE-Ⅱ的相关系数r=0.279,P=0.061没有相关性。结论腹内压监测是急性重症胰胰炎较好的临床疗效评估参数。

Objective In order to deduce the effects of intra-abdominal pressures on the severity of severe acute pancreatitis and the clinical significance of healing efficacy analysis,the data of severe acute pancreatitis patients in ICU were measuered.MethodsThe data of intra-abdominal pressures of 28 severe acute pancreatitis patients（10 patients in dead group,18 patients in healed group）were collected from May,2005 to May,2009.The relativities between intra-abdominal pressures,abdomen circumferences and APACHE-Ⅱ Scores were compared in each group.ResultsIt was obvious to correlate intra-abdominal pressures to APACHE-Ⅱ Scores（Y = 1.406＋0.690X,r= 0.646,P 0.001）,and there was some correlation between abdomen circumferences and APACHE-Ⅱ Scores（r=0.175,P=0.048） in the healed group.In the dead group it was obvious correlation between intra-abdominal pressures and APACHE-Ⅱ Scores（Y = 14.767＋0.471X,r=0.387,P=0.008）,and no relation between abdomen circumferences and APACHE-Ⅱ Scores（r=0.279,P= 0.061）.Conclusion Intra-abdoninal pressure is a preferable parameter to evaluate clinical therapeutic effect on severe acute pancreatitis patients.