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小儿肾母细胞瘤的内科治疗进展 被引量:2

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摘要 肾母细胞瘤又称wilms’瘤或肾胚胎瘤(wilm's tumor,WT),是1种复杂的胚胎性恶性混合性肿瘤,其发生是多因素、多基因参与的过程。随着对肿瘤基因水平的深入研究,发现肿瘤侵袭、浸润和转移与血管生成及细胞外基质降解密切相关。血管内皮生长因子(vacularendothelialgrowthfactor,VEGF)具有促进血管内皮细胞增殖、促进血管生成、增加血管通透性以及血管维持功能,被认为是作用最强、特异性最高的调控血管生成因子;
出处 《实用癌症杂志》 2010年第6期679-681,共3页 The Practical Journal of Cancer
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参考文献18

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二级参考文献6

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同被引文献19

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