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南蛇藤化学成分研究 被引量:7

Studies on Chemical Constituents of Celastrus orbiculatus
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摘要 采用柱色谱技术,从南蛇藤根茎95%乙醇浸膏的正丁醇部分分离得到8个苷类化合物,经MS和NMR分析,分别鉴定为3-羟甲基呋喃葡萄糖苷(1),大黄素-6-O-β-D-葡萄糖苷(2),3,4,5-三甲氧基苯酚葡萄糖苷(3),丁香酸葡萄糖苷(4),(1S,2S,4R)-1,8-反式桉叶素-2-O-(6-O-α-L-鼠李糖基)-β-D-葡萄糖苷(5),pumilaside A(6),3,4-二甲氧基苯酚-(6-O-α-L-鼠李糖基)-β-D-葡萄糖苷(7),3,4,5-三甲氧基苯酚-(6-O-α-L-鼠李糖基)-β-D-葡萄糖苷(8)。化合物1、2、4、5、6、7和8为首次从南蛇藤中得到,其中化合物2为首次从南蛇藤属植物中报道的蒽醌类化合物。 Column chromatographic technique was used for the isolation and purification of the chemical constituents of the n-butanol portion from 95% ethanol extract of the root and radix of Celastrus orbiculatus.Eight compounds were isolated and identified by means of MS and NMR spectroscopy as 3-furanmethanol β-D-glucopyranoside(1),emodin-6-O-β-D-glucopyranoside(2),3,4,5-trimethoxyphenyl-β-D-glucopyranoside(3),glucosyringic acid(4),(1S,2S,4R)-trans-1,8-cineole-2-O-(6-O-α-L-Rha)-β-D-glucopyranoside(5),pumilaside A(6),1-(α-L-rham(1→6)-β-D-glu)-3,4-dimethoxybenzenephenol(7),1-(α-L-rham(1→6)-β-D-glu)-3,4,5-trimethoxyphenol(8).Among them,compounds 1,2,4,5,6,7 and 8 were first isolated from this plant,and compound 2 was a constituent of anthraquinone first discovered from the Celastrus genus.
出处 《中国医药工业杂志》 CAS CSCD 北大核心 2010年第11期823-826,共4页 Chinese Journal of Pharmaceuticals
基金 国家"重大新药创制"科技重大专项资助(2009ZX09301-007)
关键词 南蛇藤 化学成分 结构鉴定 Celastrus orbiculatus chemical constituent structure identifi cation
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参考文献10

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二级参考文献16

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