摘要
目的观察六月青(Liuyueqing,LYQ)体外抗乙型肝炎病毒(HBV)的作用。方法采用血清药理学方法,在HBV的体外细胞培养系统中(2.2.15细胞)进行LYQ抗HBV cccDNA作用观察。结果 LYQ含药血清在HepG2.2.15细胞培养中可有效地抑制细胞HBV cccDNA的复制,其作用呈明显的量效和时效反应关系。结论 LYQ在体外有明显的抑制乙肝病毒的作用。
Objective To study the anti-HBV activity of Liuyueqing（LYQ） in vitro.Methods The HBV in vitro cell culture system（HepG2.2.15 cell） was used for examining the anti-HBV activity of LYQ with Serum-pharmacology.Results The serum containing LYQ could decrease the HBV DNA level in HepG2.2.15 cells,and its inhibitory effects were dose-and time-dependent.Conclusion LYQ can inhibit HBV DNA in vitro significantly.
出处
《时珍国医国药》
CAS
CSCD
北大核心
2010年第11期2747-2748,共2页
Lishizhen Medicine and Materia Medica Research
基金
广西壮族自治区教育厅自然科学基金(No.200710MS014)
