复方甘露醇注射液组方的筛选

Selecting the Best Preparation or Compound Mannitol Injections

采用家兔颈内动脉注射橄榄油致急性脑水肿的方法制作家兔急性脑水肿模型，观察了不同组份的复方甘露醇注射液与20％甘露醇注射液对家兔急性脑水肿的作用。结果显示：各级复方甘露醇注射液均有明显的脱水与利尿作用（与20％甘露醇比较，P＞0.05；与0.09％氯化钠比较，P＜0．05），并提示组方Ⅰ、Ⅱ和Ⅲ脱水作用较好，组方Ⅲ的利尿作用最强。

Injecting the olive oil into one side internal carotid artery, it produced the acute experimentalbrain edema in rabbits. Then observed and compared the effect of different compound mannitol injections with20% mannitol on acute experimental brain edema in rabbits. The results showned the deprivation and diuresis ofevery comPOund mannitol injection were abvious(comparing with 20% mannitol, P > 0. 05; comparing with 0.9 % ndium chloride, P < 0.05 ),and the results suggested that the compoLind edtol - I IIand IIIwere better.