血糖和糖化血清蛋白在急性颅脑损伤患者的检测价值

THE TESTING VALUE OF BLOOD GLUCOSE AND GLYCOSYLATED SERUM PROTEIN IN ACUTE CRANIOCEREBRAL LNJURY PATIENTS

目的:通过检测急性颅脑损伤后血糖(Glu)和糖化血清蛋白(GSP)水平变化,探讨其检测价值。方法:检测了31例糖尿病颅脑损伤患者和47例无糖尿病颅脑损伤患者Glu、GSP水平变化,并与30例健康对照组做了比较。结果:糖尿病组和无糖尿病组颅脑损伤患者血糖水平均显著高于对照组(P<0.01);糖尿病组患者GSP水平显著高于无糖尿病颅脑损伤组和对照组,无糖尿病颅脑损伤组的GSP水平与对照组相比差异无显著性(P>0.05)。无糖尿病急性颅脑损伤患者入院时和痊愈出院时比较血糖水平差异有显著性(P<0.01);GSP水平差异无显著性(P>0.05)。结论:Glu检测可以作为急性颅脑损伤患者监测病情,评估预后具有重要临床使用价值。GSP检测可以作为鉴别急性颅脑损伤患者血糖增高是应激性还是糖尿病性重要依据,也可作为检测急性颅脑损伤患者是否有糖尿病的一种方法。

Objective：Through testing the changes of blood glucose（Glu） and glycosylated serum protein（GSP） levels after acute craniocerebral injury explore the testing value.Methods Test the changes of blood glucose and glycosylated serum protein levels of 31 craniocerebral injury patients with diabetes and 47 craniocerebral injury patients without diabetes and compare with 30 cases in healthy control group.Results The glucose levels of diabetes group and no diabetes group are both higher than control group（P0.01）;GSP level in diabetes group is significantly higher than no diabetes group and control group and there is no significant difference between GSP levels of no diabetes group and control group（P0.05）.When acute craniocerebral injury patients without diabetes were hospitalized and left hospital cured,glucose levels had significant difference（P0.01）;GSP levels had no significant difference（P0.05）.Conclusion Glucose testing has important clinical value to monitor acute craniocerebral injury patients and evaluate prognosis.GSP testing can be taken as a foundation to differentiate that if acute craniocerebral patients＇ glucose heightened,diabetic.GSP testing can also be a method to test if acute craniocerebral injury patients have diabetes.