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珠蛋白生成障碍性贫血的基因诊断 被引量:2

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摘要 珠蛋白生成障碍性贫血(thalassemia,Th)又称地中海贫血,是一类常见且严重的遗传性血液疾病。该病由于珠蛋白基因突变,使组成血红蛋白(Hb)分子的α珠蛋白肽链或β珠蛋白肽链的合成缺乏或减少而导致溶血性贫血[1]。若α珠蛋白肽链合成缺乏,称α-Th,若β珠蛋白肽链合成受到抑制,称β-Th。
出处 《诊断学理论与实践》 2010年第5期405-408,共4页 Journal of Diagnostics Concepts & Practice
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参考文献9

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共引文献2

同被引文献21

  • 1沈晓明,王卫平.儿科学[M].北京:人民卫生出版社,2008:199.
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  • 8陈晨春,(综述),仇小强(审校).α-地中海贫血流行状况[J].中国妇幼保健,2009,24(6):858-861. 被引量:9
  • 9李军,殷和.地中海贫血的诊断技术及进展[J].重庆医学,2009,38(7):864-866. 被引量:31
  • 10李彬,彭常军.β-地中海贫血的基因分布及其血常规参数变异分析[J].临床血液学杂志(输血与检验),2009,22(2):183-184. 被引量:9

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