尿液基细胞学与传统细胞学对膀胱癌诊断价值的比较

Comparison of urine liquid-based cytology and conventional cytology in diagnosis of bladder cancer

目的:评估尿液基细胞学(LBC)与传统细胞学(CC)在膀胱癌诊断中的应用价值。方法:对208例膀胱癌疑似患者的尿液进行液基细胞学和传统细胞学涂片检查,结果与组织病理学结果对照,对比上述两种方法对膀胱癌诊断的敏感度、特异度;并分析两种方法的涂片质量和检出的癌细胞的形态结构。结果:尿液基细胞学与传统细胞学检出分别为:癌细胞(108次、102次),可疑癌细胞(51次、39次),非典型细胞(32次、41次);尿液基细胞学与传统细胞学的敏感度分别为71.7%、65.0%;特异度均为99.3%。结论:尿液基细胞学对膀胱癌诊断比传统细胞学更准确,液基细胞学涂片质量更佳。

Objective：To evaluate the clinical value of urine liquid based cytology and conventional cytology in the diagnosis of bladder cancer.Methods： Urine samples from 208 patients with suspected badder caner were detected by liquid based cytology and conventional cytology respectively,results were compared to histopathology.Results： Total of 108 times urine samples from 208 patients of liquid based cytology were detected in cancer cells,51 times were suspicious cancer cells,32 times were atypical cells;102 times of conventional cytology were detected in cancer cells,39 times were suspicious cancer cells,52 times were atypical cells.The sensitivity for liquid based cytology and conventional cytology was 71.7 %,65.0% respectively;both of specificity was 99.3%.Conclusion： Liquid based cytology facilitate a more accurate diagnosis than conventional cytology in diagnosis of bladder cancer,the quality of liquid based cytology smear is better than conventional cytology.