摘要
目的探讨鼻腔鼻窦嗅神经母细胞瘤的临床特点及诊断治疗方法。方法回顾性分析本院2000年1月至2006年12月收治7例嗅神经母细胞瘤患者临床表现、诊断和手术径路、预后。结果本组手术+放疗及化疗7例,2例1年内复发。复发病例经再次放疗及化疗,随访1年,1例死亡,1例带瘤生存。结论嗅神经母细胞瘤早期诊断困难。行鼻内窥镜下经额鼻联合径路切除是较理想的手术方式。术后联合放疗及化疗十分重要。
Objective To discuss the clinical characteristics, diagnosis and treatment of esthesioneuroblastoma (ENB). Methods The clinical data of 7 patients with ENB were analyzed retrospectively, and the clinical characteristics, diagnosis, surgical approaches and prognosis of the disease were discussed. Results The 7 patients received surgical treatment combined with radiotherapy and chemotherapy. Tumor relapse occurred within one year in two cases, which were treated with a second operation combined with radiotherapy, and one patient died and one survived with tumor after a one-year follow-up. Conclusion Early diagnosis of ENB can be difficult. Transnasal-frontal approach with nasal endoscope is effective approach to ENB treatment, and the patients may benefit from postoperative radiotherapy and chemotherapy to improve the prognosis.
出处
《南方医科大学学报》
CAS
CSCD
北大核心
2010年第10期2402-2403,2405,共3页
Journal of Southern Medical University
关键词
嗅神经母细胞瘤
化疗
放疗内窥镜检查
esthesioneuroblastoma
radiotherapy
chemotherapy
endoscopy