泰州市2009年麻疹减毒活疫苗初免成功率调查分析

Analysis on Immune Successful Rate of Measles Attenuated Live Vaccine among Infants in Taizhou 2009

目的了解泰州市婴儿麻疹疫苗接种后的免疫成功率情况,为消除麻疹提供参考依据。方法2009年7-8月在姜堰市2个镇对60名满8月龄婴儿,在麻疹疫接种前、接种后1个月分别采集1份血清标本进行抗体滴度检测。结果60名婴儿接种麻疹疫苗前抗体阳性者3名,阳性率5%;接种麻疹疫苗后1个月,抗体阳转率100%。结论泰州市麻疹疫苗接种有效,抗体阳转率高,免疫前抗体阳性者接种麻疹疫苗后可增加抗体滴度。有效保护儿童免受麻疹病毒的侵袭。

Objective To analyze the immune successful rate of immunization of measles vaccine among infants in Taizhou and provide evidence for specific strategies and measures of measles prevention and control.Methods During June-August,2009,60 infants aged 8 months were selected to have measles antibody test among two towns in Jiangyan,the first blood sample was taken before the vaccination and the second one was taken 30 days after vaccination for the antibody titer detection.Results Among 60 infants,4 were measles antibody-positive before vaccination（5%）.One month after the vaccination,the positive seroconversion rate was 100%.Conclusion The measles vaccination in Taizhou was effective with high positive seroconversion rate.The vaccination of the children who were antibody positive before the vaccination could increase the antibody titer,which would benefit the children＇s health by blocking-up the infection of measles virus.