高敏C-反应蛋白早期诊断妊娠期糖尿病的临床意义被引量：3

Clinical value of high sensitive C-reactive protein in early diagnosing gestational diabetes mellitus

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摘要目的：探讨高敏C-反应蛋白（hs-CRP）对妊娠期糖尿病诊断的临床意义。方法：对2009年311月在广州市第一人民医院就诊孕2428周孕妇行GCT筛查,GCT异常孕妇行75 g OGTT检测。采用免疫透射比浊法检测GCT正常孕妇组（30例）和GCT异常孕妇组（95例）的hs-CRP水平。结果：GCT正常孕妇hs-CRP阳性率为16.7%,GCT异常孕妇组hs-CRP阳性率为51.6%,GCT正常与异常组hs-CRP水平存在统计学差异（P〈0.05）。95例GCT异常孕妇根据葡萄糖耐量试验（OGTT）诊断,妊娠期糖尿病（GDM）18例,葡萄糖代谢耐受不良（IGT）13例,OGTT组64例,其hs-CRP阳性率分别为55.6%、53.8%、50.0%,差异无统计学意义。GDM组和IGT组大部分孕妇（64.7%的）hs-CRP水平高于〉10 mg/L。结论：高水平的hs-CRP是GDM的高危因素,hs-CRP可作为妊娠期糖尿病早期诊断的指标。 Objective：To explore the clinical value of high sensitive C-reactive protein in diagnosing gestational diabetes mellitus.Methods：To measure the level of high sensitive C-reactive protein for 30 samples from normal pregnancy women group and 95 samples from gestational diabetes mellitus group.Results：The level of high sensitive C-reactive protein in gestational diabetes mellitus group was significant higher than that in normal pregnancy women group（P〈0.05）.Conclusion：High sensitive C-reactive protein in serum may be used to diagnose and detect gestational diabetes mellitus.

作者廖军张玉洁吴瑜霞

机构地区广东省广州市第一人民医院检验科广州市第一人民医院妇产科

出处《中国妇幼保健》 CAS 北大核心 2010年第32期4764-4766,共3页 Maternal and Child Health Care of China

基金广东省医学科研基金〔A2008510〕

关键词高敏C-反应蛋白妊娠期糖尿病早期诊断 High sensitive C -reactive protein Pregnancy gestational diabetes mellitus Early diagnosis

分类号 R714.256 [医药卫生—妇产科学]

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参考文献11

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