抗HBc阳性在乙肝5项指标中的分布及滴度关系

Predictive value of positive anti-HBcAb in hepatitis B infection

目的:观察抗HBcAb阳性在各种乙肝5项模式的分布情况及其滴度关系。方法:选取中山大学附属中山医院检验医学中心2009年用ELISA法检验HBcAb阳性的乙肝5项结果进行分析统计。结果:乙肝5项模式共有9种,常见模式7种,其中"135、145、15"占总抗HBcAb阳性数的62.3%;"25、245、45、5"占总抗HBcAb阳性数的37.6%。高浓度的HBcAb阳性特别是其S/CO值<0.1且HB-sAg检出阳性的模式占41.3%。结论:HBcAb阳性特别是其高滴度时存在乙型肝炎病毒感染的风险大,应重视及正确分析处理HBcAb阳性的检验结果。

Objective：To investigate the prevalence of positive anti-HBcAb and its titers in hepatitis B infection.Methods：Results of HBSAg,HBSAb,HBEAg,HBEAb,and HBCAb detected with ELISA during 2009 in Center of Laboratory Medicine,Zhongshan Hospital Affiliate to Zhongshan University were statistically analyzed.Results：There were nine kinds of results,of which 7 were commonly found.Specifically,62.3% HBCAb（＋）was co-existed with ＂HBSAg（＋）,HBEAg（＋）,HBCAb（＋）＂,＂HBSAg（＋）,HBEAb（＋）,HBCAb（＋）＂ and ＂HBSAg（＋）,HBCAb（＋）＂,and the left 37.6% HBCAb（＋）presented in ＂HBSAb（＋）,HBCAb（＋）＂,＂HBSAb（＋）,HBEAb（＋）,HBCAb（＋）＂ ＂HBEAb（＋）,HBCAb（＋）＂.Besides,HBcAb（＋）at high titles,especially where S/CO 0.1 HBsAg,41.3% were diagnosed as hepatitis B infection.Conclusions：HBcAb（＋）,especially at high titles,indicates high risk of hepatitis B infection,and should be treated with great caution.