宫颈微偏腺癌1例临床病理分析及文献复习

A clinicopathological study on minimal deviation adenocarcinoma of uterine cervix

目的探讨子宫颈微偏腺癌的临床特征、病理组织学形态、诊断及鉴别诊断。方法通过总结本病例及复习相关的文献资料,分析该病例的临床特征、组织形态学和免疫染色特点。结果微偏腺癌患者白带增多呈水样,子宫颈肥大呈桶状,镜下见宫颈腺体均大小不等、形状怪异,扭曲如爪状或尖角突出。结论宫颈微偏腺癌罕见,早期确诊率低,易误诊,病理形态观察、免疫组化染色对诊断及鉴别诊断有重要意义。

Objective To investigate the clinical features,pathologic morphology,initial and different diagnosis of minimal deviation adenocarcino-ma（MDA） in the cervix. Methods There is 1 case reported and some literatures reviewed here to discuss the clinical manifestations,pathomorphological changes and immunohistochemical expressions of MDA of the uterine cervix.Results The important clinical symptoms were watery leucorrhea and enlarged cervix.Histologically,the glands were characterized by irregular shapes,twisted and feeling like chicken claw.Conclusion MDA is rare and prone to be missed-early diagnosed and misdiagnosed,the investigations of pathomorphology and IHC results are significant for its diagnosis and differential diagnosis.