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癌症诊断和治疗的潜在靶标——PCDGF 被引量:1

PCDGF,a potential target for the diagnosis and treatment of cancer
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摘要 畸胎瘤细胞源性生长因子(PCDGF)是一种自分泌生长因子,其是生长调节因子家族中的成员,以分子中含有一个独特的半胱氨酸富集区为特征。PCDGF参与多种肿瘤的发生、侵袭及细胞存活,提示其可能成为癌症诊断和治疗的一个合适的靶标。 PC-cell derived growth factor (PCDGF)is an autocrine growth factor. It is a family member of growth modulators and characterized by a unique cysteine-rich motif. PCDGF participates in carcinogenesis, invasion and survival. It could be suggested to serve as a suitable target in the diagnosis and treatment of cancer.
出处 《世界临床药物》 CAS 2010年第11期682-686,共5页 World Clinical Drug
基金 国家"重大新药创制"科技重大专项(2009ZX09301-007)
关键词 畸胎瘤细胞源性生长因子 肿瘤发生 自分泌生长因子 乳腺癌 PC-cell derived growth factor tumorigenesis autocrine growth factor breast cancer
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