摘要
目的 对3例因生食青蛙致广州管圆线虫感染的病例进行研究分析,探讨广州管圆线虫病的感染途径和流行特点。方法 从2006-2010年深圳市疾病预防控制中心寄生虫门诊检测出的42例广州管圆线虫IgG抗体阳性病例资料中整理出3例因接触蛙类而感染本病的病例,对其流行病学资料、临床表现、血中嗜酸性粒细胞浓度、病变部位CT及MRI和血清免疫学特征进行研究分析。结果 接触青蛙的3例广州管圆线虫病例均为广东本地感染,因生食青蛙或用蟾蜍肉贴敷疮疡而感染。临床表现主要为发热和头痛。3例循环抗原CAg均为阳性,其中1例10 d前生食青蛙者IgM抗体阳性。而肝吸虫、肺吸虫、包虫、囊虫、弓形虫和裂头蚴抗体均为阴性。结论 接触蛙类是广州管圆线虫病感染的重要途径,感染后出现典型的临床症状和血清学特征。
Objective To investigate the epidemic characteristics of Angiostrongyiasis cantonensis infection through the contact with frogs.Methods Three cases of Angiostrongyiasis cantonensis infection caused by contacting with frogs were selected from the 42 cases with serological positive reaction to A.cantonensis IgG antibodies.Diagnosis was performed in the parasitology clinics,Shenzhen Center of Diseases Control(CDC) from 2006 to 2010.The epidemic data,clinical manifestations,eosinophils concentration in blood,CT and MRI scanning of the infected sites and serological data were analyzed.Results All the three patients were from Guangdong provinces.The infection was correlated with the consumption of raw frog meat or covering the wound with raw hop toad meat.The clinical manifestations of these three cases were fever and headache.All of them showed CAg positive.One of the patients showed positive IgM at 10 days after consumption of the raw frog meat.Further serological analysis indicated that the patient was sero-negative to the antigens of Clonorchis sinensis,Paragonimus westernami,hydatid,bladder worm,Toxoplasma and Sparganum..Conclusions Contacting with frogs can cause Angiostrongyiasis cantonensis infection.Typical clinical symptom and serological characteristics are found after the infection.
出处
《热带医学杂志》
CAS
2010年第10期1218-1220,共3页
Journal of Tropical Medicine
基金
广东省自然科学基金(No.8151802003000002)
关键词
广州管圆线虫病
蛙
流行病学
嗜酸性粒细胞
血清学
Angiostrongylus cantonensis
frogs
epidemiology
eosinophile granulocyte
serology