离子液体[Hmim]BF_4催化合成β-烯胺酮类化合物

Preparation of imidazolium ionic liquids and their catalytic activity in the synthesis of β-enaminones

合成了一系列具有不同阴离子的[Hmim]+咪唑型离子液体,并考察了催化剂在β-烯胺酮合成中的催化性能.结果表明,[Hmim]+咪唑型离子液体对β-烯胺酮合成具有高的催化活性,其中[Hmim]BF4活性最高,反应时间为10 min,产率可达96%;将该催化剂用于催化不同底物的β-烯胺酮化合物的合成,多数反应显示了优良的催化性能.离子液体[Hmim]BF4重复使用5次,催化活性基本不变,反应10 min后,β-烯胺酮产率仍有89%.

a series of imidazolium ionic liquids （ [ Hmim] ＋ ） with different anions were prepared and the catalytic performance of these catalysts for the synthesis of β-enaminones were investigated. The results showed that these [ Hmim] ＋-type ionic liquids exhibited excellent activity. [ Hmim] BF4 had the best catalytic performance and had a yield of 96% after 10 rain. [ Hmim] BF4 as a catalyst has been used for the synthesis of different β-enaminones and most of the reactions can proceed smoothly. [ Hmim] BF4 was reused five times without considerable loss of activity and had a yield of 89% after 10 rain reaction.