利普液基细胞学(LPT)在宫颈病变诊断中的价值

The Application of Liquid-Prep Test in the Diagnosis of Cervical Lesion

目的:探讨利普超薄液基细胞学制片技术(Liquid-Prep Test,LPT)在宫颈病变中的应用价值。方法:7 000例患者接受LPT宫颈液基细胞学检查。部分结果异常者做阴道镜检查或宫颈多点活检进行组织病理学检查对照。结果:92例LPT宫颈细胞学检查与组织病理学对照结果显示:鳞状细胞癌(SCC)符合率最高,为100%(9/9),其次鳞状上皮内高度病变(HSIL)为90.91%(20/22),鳞状上皮内低度病变(LSIL)为72.41%(21/29)。腺癌(AC)为100%(1/1)。结论:LPT液基细胞学检查的敏感性高,它能准确地反映宫颈癌和癌前病变,是一种有效的宫颈癌的筛查手段。

Objective： To evaluate the effects of Liquid-prep test （LPT） used in cervical lesions. Methods： LPT cervical cytology test was made in 7000 patients. The colposcopy or multi-spots biopsies for histopathology inspection were performed in partial patients with abnormal results to compare and analyze the cytology results and histopathology diagnosis. Results： The comparative results of cervi- cal cytological Liquid-prep test and histopathology in 92 cases showed that： coincidence rate in squamous cell carcinoma （SCC） was 100% （9/9）, in hlgh-grade squamous intraepithelial lesion （HSIL） was 90. 91% （20/22）, in low-grade squamous intraepithelial lesion （LISL） was 72. 41% （21/29）, and in adenocarcinoma （AC）was 100% （1/1）. Conclusion： The cytology Liquid-prep test has high sensitivity for cervical lesion. LPT is an effective screaming technique which can diagnose cancer and per-cancer diseases accurately.