络活喜对高血压患者动态血压及并发症的影响

The Effect of Norvasc on Ambulatory Blood Pressure and Compliction of the Patients with Hypertension

目的探讨络活喜对高血压患者动态血压及心脑血管并发症的影响。方法 60例高血压患者分别采用络活喜及硝苯地平缓释片治疗,并在治疗前后及治疗过程中进行动态血压监测,在治疗结束后统计60例患者心、脑血管并发症发生情况。结果络活喜治疗2年后有效率93.3%,无效率6.7%,硝苯地平缓释片治疗2年后有效率66.7%,无效率33.3%。2组相比有显著统计学差异(P<0.01)。结论与硝苯地平缓释片像比较,络活喜降压平稳,不良反应小,并且能减少心、脑血管并发症。

Objective To investigate the effect of Norvasc on ambulatory blood pressure and complication of patients with hypertension.Methods Sixty patients with hypertension of second grade who took Norvasc and Nifedipine retard tablets orally were monitored for ambulatory blood pressure and cardiovascular and cerebrovascular complication.Results After two year＇streatment,the effective and ineffective rates of Nornasc were 93.3%and6.7%respectively,and the effective and ineffective rates of Nifedipine were 66.7% and 33.3% respectively（P0.01）.Conclusion Norvasc can control the blood pressure stablely,and reduce the cardiovascular and cerebrovascular complication.