新生儿呼吸机相关性肺炎病原学分析

Etiologic analysis of neonatal ventilator-associated pneumonia

目的:探讨新生儿呼吸机相关性肺炎(VAP)的病原学特点及防治措施。方法:对本院2007年1月～2009年6月新生儿抢救室采用呼吸机机械通气的患儿60例,对其气道分泌物进行病原学培养分析及药敏试验。结果:该组患儿中发生VAP23例,发生率为38.3%,革兰阴性菌是主要的致病菌,且对主要的抗生素有广泛抗药性。结论:明确VAP的发病因素,提高预防意识,加强无菌操作,合理地选择抗生素,是降低VAP死亡率的关键。

Objective：Investigate the pathogenic characteristics and control measures of neonatal ventilator-associated pneumonia（VAP）.Methods：Slected 60 cases of children with mechanical ventilation in our hospital from January 2007 to June 2009 emergency room with neonatal ventilator,airway secretions of their culture and susceptibility test pathogen.Results：23 cases occurred VAP,the rate was 38.3%,gram-negative bacteria was a major pathogen,and a wide range of major antibiotic resistance.Conclusion：Definite the incidence factors of VAP to improve prevention awareness,strengthen aseptic operation,reasonable choice of antibiotics is the key to reducing VAP mortality.