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SDF-1/CXCR7轴与肿瘤的研究进展 被引量：8

Research Progress in SDF-1/CXCR7 Axis and Cancer
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摘要 基质细胞衍生因子-1(SDF-1)及其受体CXCR4所构成的SDF-1/CXCR4生物轴在肿瘤发生、发展及肿瘤血管新生中发挥重要作用。最近研究发现CXCR7也是SDF-1的受体,且与肿瘤密切相关。全文就SDF-1新受体CXCR7的生物学特征,SDF-1/CXCR7轴在肿瘤细胞中的表达,SDF-1/CXCR7轴与肿瘤细胞增殖和存活、肿瘤侵袭和转移以及肿瘤血管新生的关系作一综述。
作者 郑芳 李慧玉 黄士昂
机构地区 华中科技大学同济医学院
出处 《肿瘤学杂志》 CAS 2010年第9期740-743,共4页 Journal of Chinese Oncology
基金 国家自然科学基金(30971112)
关键词 CXCR7 SDF-1 肿瘤 趋化因子
分类号 R730.5 [医药卫生—肿瘤]
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参考文献22

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同被引文献102

  • 1曾东风,孔佩艳,陈幸华,彭贤贵,魏立,常诚,刘林,刘红,王庆余.SDF-1及其受体CXCR4在急性白血病与淋巴瘤表达的初步研究[J].中国实验血液学杂志,2005,13(2):274-277. 被引量：29
  • 2陈日玲,蔡康荣,陈铭珍,张慧琼,方希敏.CXCR4在急性白血病细胞中的表达及其意义[J].实用儿科临床杂志,2005,20(9):879-880. 被引量：7
  • 3王晓颖,樊嘉,周俭,邱双健,余耀,刘银坤,汤钊猷.CCR1趋化因子受体在人肝癌组织中表达及其临床意义[J].中华肝胆外科杂志,2006,12(2):101-104. 被引量：20
  • 4戴永援,陈宝安.SDF-1/CXCR4与血液系统恶性肿瘤的关系研究进展[J].中国实验血液学杂志,2006,14(5):1056-1060. 被引量：2
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  • 7Salmaggi A, Madema E, Calatozzolo C ,et al. CXCL12, CXCR4 and CXCR7 expression in brain metastases. Cancer Biol Ther, 2009; 8 (17) : 1608 -1614.
  • 8lwasa S, Yanagawa T, Fan J, et al. Expression of CXCR4 and its ligand SDF-1 in intestinal-type gastric cancer is associatedwith lymph nodeand liver metastasis. Anticancer Res, 2009; 29 (11 ) : 4751 - 4758.
  • 9Voermans C, van Heese WP, de Jong I, et al. Migratory behavior of leukemic cells from acute myeloid leukemia patients. Leukemia, 2002;16(4) : 650 -657.
  • 10Crazzolara R, Kreczy A, Marlin G,et al. High expression of chemo- kine receptor CXCR4 predicts extrameduUary organ infiltration in childhood acute lymphoblactic leukemia. Br J Haematol, 2001; 115 (3) : 545 -553.

引证文献8

二级引证文献24

肿瘤学杂志
2010年 第9期

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