2005—2009年东莞市东华医院抗糖尿病药使用情况分析

Utilization of Antidiabetic Drugs from 2005 to 2009 in Donghua Hospital of Dongguan

目的:分析东莞市东华医院2005—2009年抗糖尿病药的使用情况及用药趋势。方法:用金额排序法及DDD分析法统计5年来抗糖尿病药在我院的消耗情况、品种分布及用药费用,作为分析判断药物使用情况指标,分析临床糖尿病患者的用药状况。结果:近5年来,我院抗糖尿病药用药金额和用药频率(用药/人次)均有大幅度的增长(口服及注射剂用药金额增幅分别为132.04%和144.46%,且用药频率增幅分别为126.40%和144.46%)。用药金额排序前3位为α-糖苷酶抑制剂、磺酰脲类和双胍类;用药频率(用药/人次)排序前3位为α-糖苷酶抑制剂、磺酰脲类和促进胰岛素分泌剂,阿卡波糖使用最多且同步性好。胰岛素使用均在20%以下,以短效胰岛素使用为主。结论:5年间糖尿病患者口服抗糖尿病药使用较多,其中α-糖苷酶抑制剂的使用占主导地位,胰岛素使用有待提高。

OBJECTIVE：To evaluate the utilization of antidiabetic drugs in our hospital from 2005 to 2009.METHODS：With the method of ordering of consumption sum and analysis on DDDs,the utilization of antidiabetic drugs from 2005 to 2009 in our hospital was analyzed in respect of consumption,categories of drugs and drug costs.RESULTS：From 2005 to 2009 in our hospital,the consumption sum and DDDs of antidiabetic drugs witnessed a sharp increase,up 132.04% for oral antidiabetic drugs and 144.46% for injections of antidiabetic drugs in terms of consumption sum,and up 126.40% for oral antidiabetic drugs and 144.46%（injections） in terms of DDDs.Leading the first 3 places in terms of consumption sum were α-glucosidase inhibitors,Sulfonylurea and Metformin respectively;leading the first 3 places in terms of DDDs were α-glucosidase inhibitors,Sulfonylurea and insulin secretion promoting agents,with Acarbose taking the lead in consumption and which showed a good synchronism.The use of insulin accounted for lower than 20%,in which,the type with short-term efficacy took the lead.CONCLUSION：Over the five years,the consumption of oral antidiabetic drugs was on the high side,much as in the consumption of αglucosidase inhibitors,thus the rational use level of the insulin remains to be elevated