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2007—2009年北京儿童医院闭塞性细支气管炎患儿治疗回顾 被引量:2

Treatment of Children with Bronchiolitis Obliterans in Beijing Children's Hospital During the Period of 2007-2009:Retrospective Analysis
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摘要 目的:总结分析闭塞性细支气管炎住院患儿药物治疗经验,为临床提供参考。方法:对北京儿童医院2007年1月—2009年12月收治的闭塞性细支气管炎病例进行回顾性调查,分析其药物治疗情况和预后。结果:96.8%的闭塞性细支气管炎患儿使用了糖皮质激素;88.7%使用了支气管舒张剂;32.2%使用了大环内酯类抗菌药物。绝大多数患儿病情好转出院。结论:糖皮质激素联合支气管扩张剂及大环内酯类药物是儿童闭塞性细支气管炎的主要治疗药物。但该病治疗困难,大多预后不良。 OBJECTIVE: To analyze our experiences with the treatment of patients with bronchiolitis obliterans in our hospital for clinical reference. METHODS : In this retrospective study, the medical records of pediatric patients with bronchiolitis obliterans admitted to our hospital from Jan. 2007 to Dec. 2009 were analyzed regarding the medication and prognosis. RESULTS: Of all the cases reviewed, 96.8% used glucocorticoid; 88.7% used bronchodilators and 32.2% used macrolide antibiotics. The majority took a favorable turn and were discharged from the hospital. CONCLUSION: The predominant drugs for pediatric patients with bronchiolitis obliterans were glucocorticoid, bronchodilators and macrolide antibiotics. This disease is hard to cure with poor prognosis in most cases.
出处 《中国医院用药评价与分析》 2010年第11期1004-1005,共2页 Evaluation and Analysis of Drug-use in Hospitals of China
关键词 闭塞性细支气管炎 儿童 药物治疗 Bronchiolitis obliterans Children Medication
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  • 1Zhang LJ, Irion K, Kozakewich H, et al. Clinical course of postinfectious bronchiolitis obliterans [J]. Pediatr Pulmon, 2000, 29:341-350.
  • 2Kurland G, Michelson P. Bronchiolitis obliterans in children [J]. Pediatr Pulmonol, 2005, 39: 193-208.
  • 3Konen E, Gutierrez C, Chaparro C, et al. Bronchiolitis obliterans syndrome in lung transplant recipients: can thin-section CT findings predict disease before its clinical appearance? [J]. Radiology, 2004, 231:467-473.
  • 4Yalcin E, Dogru D, Haliloglu M, et al. Postinfectious bronchiolitis obliterans in children: clinical and radiological profile and prognostic factors [J]. Respiration, 2003, 70: 371-375.
  • 5Teper A, Fischer GB, Jones MH. Respiratory sequelae of viral diseases: from diagnosis to treatment [J]. J Pediatr, 2002, 78: 187-194.
  • 6Verleden GM, Dupont LJ. Azithromyein therapy for patients with bronchiolitis obliterans syndrome after lung transplantation [J]. Transplantation, 2004, 77 : 1465-1467.
  • 7Zhang LJ, Silva FA. Bronchiolitis obliterans in children [J]. J Pediatria, 2000, 76 : 185 - 192.
  • 8Adam J,Andew B.Anti-inflammatory effect of macrolides in lung disease[J].Pediatric Pulmouology,2001,31:464-473.
  • 9Terence ABS.Tom MAW,John RH,et al.Long-term erythromycin thcmpy is associated with decreased chronic obstructive pulmonary disease exacerbations[J].Am J Respir Crit Care Med,2008,178:1339-1147.
  • 10Oda H,Kadota J,Kahno S,et al.Erythromycin inhibits neutrophil chemotaxis in bronchoalveoli of diffuse panbronchiolitis[J].Chest,2004,106:1116-1123.

共引文献128

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  • 1赵顺英.闭塞性细支气管炎的诊治[J].中国实用儿科杂志,2006,21(4):241-243. 被引量:23
  • 2王维,申昆玲.儿童闭塞性毛细支气管炎的研究进展[J].中华儿科杂志,2006,44(4):274-277. 被引量:30
  • 3彭芸,马大庆,孙国强,曾津津.儿童闭塞性毛细支气管炎影像学表现[J].中华放射学杂志,2006,40(7):752-755. 被引量:29
  • 4Teper A, Fischer GB, Jones MH. Respiratory sequelae of viral diseases : From diagnosis to treatment [ J ]. J Pediatr ( Rio J ), 2002,78 ( suppl 2 ) : 187 - 194.
  • 5Lau CL,Zhao Y,Kron IL,et al. The role of adenosine A2A receptor signaling in bronchiolitis obliterans [ J ]. Ann Thorac Surg, 2009,88 ( 4 ) : 1071 - 1078.
  • 6Champs NS, Lasmar LM, Camargos PA ,et al. Post - infectious bronchiolitis obliterans in children [ J ]. J Pediatr ( Rio J), 2010,87 ( 3 ) : 187 - 198.
  • 7Yilmaz O, Sava R, Sogut A, et al. Effectiveness of magnetic resonance angiography in the evaluation of lung perfusion in constrictive bronchiolitis obliterans [ J ]. Respirology ,2009 ,14 (2) :295 - 298.
  • 8Mattiello R, Sarria EE, Mallol J, et al. Post - infectious bronchiolitis obliterans:Can CT scan findings at early age anticipate lung function [ J ] .9 Pediatr Pulmonol, 2010,45 (4) : 315 - 319.
  • 9Yuksel H,Yilmaz O,Urk V,et al. Clinical significance of lung perfusion defects in children with post -infectious bronchiolitis obliterans[ J]. Tuberk Toraks ,2009,57 (4) :376 - 382.
  • 10Ryu JH, Myers JL, Swensen SJ. Bronchiolar disorders [ J ]. Am J Respir Crit Care Med,2003,168( 11 ) : 1277 - 1292.

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